SP10.6 Comparison of clinicopathological features of colorectal cancer during and after lockdown

Abstract

Abstract Aims When the UK entered the lockdown, the cancer pathways changed in order to deal with the pandemic and protect cancer patients who are at high risk from the virus. The objective of our study is to compare the clinicopathological features of colorectal cancer (CRC) during and after lockdown. Methods Patients who underwent colorectal surgeries for CRC between Feb-2020 to Aug-2022 were included in the study. All patient related and disease specific details were obtained from the prospectively collected database. Patients were divided in to two groups: Surgeries before (group-A: during lockdown) and after 22/2/21 (group-B: after lockdown). Patient demographics and pathological details were collected and analysed using standard statistical tests. Results A total of 528 patients underwent surgeries during this period, of which 422 had cancer resections. During lockdown 187 patients had cancer resections (Group-A) and 235 patients had surgery for cancer after lockdown (Group-B). The median age of patients is 72 and 73 years in group-A and B respectively (p-value:0.29). There is no difference between the two groups with respect to tumour, nodal staging and extramural vascular invasion. The median lymphnode yield is 20 (range:0-80) in group-A compared to group-B where the yield was 21 (range:0-102) (p-value:0.720). There were 44 patients with rectal cancer in group-A of which 4.55% had circumferential resection margin positivity (CRM) and 6.77% (4 of 59) of rectal cancers patients in group-B had CRM positivity (p-value:0.229). Conclusions There was no difference in clinicopathological features of patients having colorectal surgery during and after lockdown.