Abstract
The association between systemic lupus erythematosus (SLE) and thrombotic thrombocytopenic purpura (TTP) is a described but rare situation and usually occurs in cases with intense lupus activity and renal impairment. It may occur in less than 2% of patients with systemic lupus erythematosus. We present below a case of SLE that abruptly debuts an episode of PTT de aggressive course, treated in an interdisciplinary way with plasma exchanges and immunosuppressants and immunomodulators.
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