Three-dimensional black blood contrast enhanced magnetic resonance imaging in patients with acute ischemic stroke and negative susceptibility vessel sign

Abstract

PurposeThe purpose of this study was to evaluate the enhancement patterns of three-dimensional (3D) black blood (BB) contrast enhanced magnetic resonance (MR) imaging in acute stroke patients with negative susceptibility vessel sign (SVS). Materials and methodsFrom January 2014 to August 2016 we retrospectively reviewed MR imaging and MR angiography findings of patients who presented with acute stroke symptoms of less than 24 h duration. For the 394 patients enrolled, we assessed the frequency of patients who exhibited negative SVS on susceptibility weighted MR imaging (SWI) and positive enhancement in 3D BB contrast enhanced MR imaging. We subdivided the enrolled group according to whether the MR angiography findings suggested stenosis (stenosis group) or occlusion (occlusion group). Enhancement patterns on BB contrast enhanced MR imaging were compared between the two groups according to several qualitative parameters: intensity (weak or strong), morphology (linear/eccentric or round/concentric), length (focal or segmental) and multiplicity (single or multiple). ResultsSixty-two of 394 patients (15.7%) showed positive findings on BB contrast-enhanced MR imaging with negative SVS. Forty-two patients were classified into the stenosis group, and 20 patients were assigned to the occlusion group. Enhancement patterns of the stenosis group showed weak intensity, linear or eccentric morphology and focal lesion length on BB contrast enhanced MR imaging, compared to the occlusion group (P < 0.001). In contrast, enhancement patterns of the occlusion group showed strong intensity, round or concentric morphology and longer segmental lesion length, compared to the stenosis group (P < 0.001). ConclusionThree-dimensional BB contrast enhanced MR imaging in acute stroke patients with stenotic lesions and negative SVS shows enhancement patterns of linear or eccentric morphology and shorter, more focal lesions.