Abstract
To determine the mechanism for the development of segmental granular lesions along the retinal vessels in eyes with acute retinal necrosis. This was a retrospective analysis of the medical records of three eyes of three patients who were diagnosed with acute retinal necrosis that had atypical segmental granular lesions aligned along the retinal vessels. The segmental granular lesions were present on the retinal arteries and veins throughout the retina. Optical coherence tomography showed that the granular lesions protruded into the vitreous cavity. Histopathologic examinations confirmed that the lesions were made up of lymphocytes. We suggest that the granular lesions were formed by a mechanism similar to that of HTLV-1-associated uveitis. We also found that the granular lesions disappeared soon after vitrectomy.
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