This issue of Acta

Abstract

The cover photograph shows enhanced optical coherence tomography (OCT) and comes from the article by Soliman et al. in this issue. Costa and Arcieri review hypotony maculopathy, including the definition, mechanisms, clinical findings and treatment of this condition. The editorial discusses the physiological consequences of hypotony in light of Starling’s law. Sigurðsson et al. in Iceland show that topical application supplies steroids in significant concentration to the posterior segment of the rabbit eye and suggest that the topical route may replace intravitreal injections in steroid treatment for retinal disease. Paccola et al. in Brazil and the USA demonstrate that postoperative inflammation after vitrectomy may be controlled either by a single subtenon injection of triamcinolone or by conventional prednisolone eye drops. Khanna et al. in India describe 48 patients with histologically confirmed sarcoidosis involving the eye, more frequently as posterior than anterior uveitis. Soliman et al. in Copenhagen use enhanced OCT to describe different morphological patterns of diabetic macular oedema and suggest that these indicate the severity of the disease. The cover photo comes from this paper. Fosmark and associates in Oslo demonstrate that levels of hydroimidazolone, an advanced glycation end product, in the vitreous are associated with diabetic retinopathy level. This may relate to blood–retinal barrier breakdown. Joussen et al. in Germany describe the design of a multicentre study to investigate the role of heavy silicone oils in proliferative vitreoretinopathy. The results of the clinical trial will be forthcoming in Acta in years to come. You and associates in China and Germany report from the Beijing Eye Study, where 0.7% of individuals have myelinated retinal nerve fibres and this has no clinical consequence. Minami et al. in Osaka study the effect of intraocular infusion pressure in vitreous surgery in rabbits. They suggest that ganglion cells may suffer from high intraocular pressure in this situation. Kjeka and associates in Bergen find photoptic ERG useful to predict neovascularization in patients with central retinal vein occlusion. Kirwan et al. in Dublin suggest that morphine analgesia may replace general anaesthesia in children who need laser treatment for retinopathy of prematurity. Vouri and Mäntyjärvi in Turku report for the first time that colour vision may be impaired in eyes with tilted optic discs. Delyfer et al. from Bordeaux contribute case reports on cytomegalovirus retinitis following intravitreal triamcinolone injections. Georgeopoulos et al. in Athens find capsular tension rings to be useful in eyes with traumatic zonular dialysis, which need cataract surgery. Wong et al. in Hong Kong find nylon and polyglactin sutures to be satisfactory in pterygium surgery. Caines and associates in Uppsala find that children with spina bifida have a high risk of stabismus, refractive error and subnormal vision. Muen et al. in Liverpool find periventricular leukomalacia in children who present with strabismus. Yazici and Akova from Turkey suggest that dacryocystorhinostomy may be performed bilaterally at the same time. In the Perspectives in Ophthalmlogy section, Sundling and associates in Norway survey Norwegian optometrists and report on their practice patterns, referrals and the disease prevalence of their patients. Kawana et al. in Japan use OCT to evaluate anterior chamber angle recession. Margolis et al. in Cleveland show a case with macular involvement resulting from breast cancer. I hope that each reader of Acta finds something of interest in this issue. You are invited to contribute letters to the editor regarding the subjects discussed in these articles.