Abstract

The reintroduction of thiocyanate in the treatment for arterial hypertension has, in recent years, attracted wide attention. A number of investigators have attested to its effectiveness in lowering both normal and abnormally elevated blood pressures.<sup>1</sup>On the other hand, it has been stated that in a large group, thiocyanate appears to exert no more beneficial effect on hypertension than do certain so-called nonspecific measures of therapy, classed under the general heading of "psychic and sedative treatment."<sup>2</sup>We have shown in a previous study<sup>3</sup>that thiocyanate administered in the dosage frequently recommended may be accompanied by serious toxic manifestations and even death. Furthermore, the great tendency toward variability of raised blood pressures<sup>4</sup>and the not infrequent spontaneous remissions observed in the course of essential hypertension<sup>5</sup>often render the true interpretation of any so-called therapeutic endeavor particularly hazardous. It therefore seemed advisable to us that another series

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