Abstract

Lipid changes of human erythrocytes treated with adenovirus type 8, 9 and 10 have been studied with thin-layer chromatography. It has been established that each of the virus types induced several qualitative changes, which were manifested either in the disappearance of spots or in the development of new ones, as well as in the changes of Rf values and staining characteristics. These changes varied with the individual types and were different from those observed with influenza virus. The decrease of aminophosphatides and other amino acid-containing lipids characterized the effect of type 8 adenovirus. Erythrocytes treated with type 9 adenovirus displayed the highest number of spots, while the decrease of unsaturated lipids and neuraminic acid characterized the effect of type 10 adenovirus.

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