Thermoradiotherapy with curative intent - Breast, head, neck and prostate tumors

Abstract

Fractionation used involved daily hyperthermia treatments in conjunction with each radiation fraction. Radiation daily doses are progressively decreased from 180 to 100 cGy resulting in protracted treatment time that decreases the isoeffect biological equivalent dose by 15% to 25%. This decrease is compensated by the increased number of hyperthermia fractions which potentiates each radiation dose. Treatment is continued until an objective complete response is attained, or failure determined. 40 breast patients, 17 head and neck and 15 prostate patients were treated with a follow up of two to five years. All patients were early stage (III-a or less).