THERMOMECHANICS MODELING AND VISUALIZATION OF PHYSICAL EFFECTS TO IMPROVE CRYOPRESERVATION BY VITRIFICATION

Reaction behaviors in pulverized coal MILD-oxy combustion affected by physical and chemical effects of diluents

Basic theoretical propositions on physical modifying effects (vibration, ultrasonic, electromagnetic agitation, and thermal-temporal processing) on the crystallization of casting alloys are generalized. Mathematical calculations and experimental investigations have revealed that the crystallization and structure formation of casting alloys could be largely determined by the treatment technology using the physical effects during melting and casting. The physical effects on a crystallizing melt cause its strong turbulization and agitation, thereby decreasing the temperature and concentration gradients in the melt, eliminating overheating the liquid phase with respect to the solidus temperature, and breaking off dendrites (which are good crystallization seeds for overall melt volume). The evaluation of the dendrite growth during crystallization showed that splitting the dendrite grains is opposed to their coarsening under physical effects. The physical effects result in bulk crystallization with equiaxed grains without the formation of the columnar structure. The physical modifying effects promote the improvement of the quality of acquired alloys and casts made of them under the conditions of their rational application.

Plant roots have great effect on the process of soil detachment, but the contribution of the physical and biochemical effects of root on soil detachment have not been sufficiently evaluated. For the purpose to distinguish the relative contribution of the root physical effect and biochemical effect to soil erosion resistance, three kinds of treatment, soil samples without roots, dead roots and live roots, were chosen to simulate the condition of no root effect, the root’s physical effect and the root’s whole effect on the soil detachment, respectively. The Cynodon dactylon and purple soil in Three Gorges Reservoir Area in China were selected to conduct the scouring experiment under condition of five slope gradients (17.63%, 26.79%, 36.40%, 46.63% and 57.73%) and three runoff rates (1, 2 and 3 L min-1). The soil detachment process under different treatment conditions was analyzed. The effects of slope gradient and the runoff rate on soil detachment rate were also estimated for different treatment conditions and the contributions of the physical and biochemical effects of root on soil detachment were also evaluated. The results indicated that detachment rate showed a dramatically decrease initially, followed by gradual decrease until to a stable stage for all treatments. The soil detachment rate can be effectively described with the slope gradient and the runoff rate by using the power function, which was more influenced by slope gradient than by runoff rate for all the treatment conditions in this study. Plant roots could effectively diminish the soil detachment rate, and the contributions of physical and biochemical effects of root on detachment were 59.64%–82.09% and 17.91%–40.36%, with mean values of 68.92% and 31.08%, respectively. The root’s physical effect is the main reason strengthens soil erosion resistance.

Main notions on the influence of modifying physical effects (vibration, ultrasound, electromagnetic stirring, thermal-temporal treatment) on the crystallization of cast alloys are generalized. It is revealed with the help of mathematic calculations and experimental investigations that the crystallization and structure formation of cast alloys can be largely determined by the technology of treatment by physical effects during smelting and casting. Physical effects on the crystallizing melt lead to its strong turbulization and mixing, which decreases the temperature and concentration gradients in the melt, eliminates overheating of the liquid phase relative to the solidus temperature, and breaks off the dendrites, which are good crystallization seeds for the entire melt bulk. The evaluation of the dendritic growth during the crystallization showed that dividing the dendrite grains under the physical effects to the melt withstands to their coarsening. Physical effects lead to the bulk crystallization with equiaxial grains without the formation of the columnar structure. Physical modifying effects promote an increase in the quality of fabricated alloys and casts made of them with the proviso of their rational use.

Physical and Psychological Effects of Gender-Affirming Hormonal Treatment Using Intramuscular Testosterone Enanthate in Japanese Transgender Men

Chemical effects of CO2 dilution on CH4 and H2 spherical flame

A New Method of Using Physical Effects in Su-field Analysis based on Ontology Reasoning

PurposeTo systematically review existing literature on knowledge and confidence of primary care physicians (PCPs) in cancer survivorship care.MethodsPubMed, Ovid MEDLINE, CINAHL, Embase, and PsycINFO were searched from inception to July 2022 for quantitative and qualitative studies. Two reviewers independently assessed studies for eligibility and quality. Outcomes were characterized by domains of quality cancer survivorship care.ResultsThirty-three papers were included, representing 28 unique studies; 22 cross-sectional surveys, 8 qualitative, and 3 mixed-methods studies. Most studies were conducted in North America (n = 23) and Europe (n = 8). For surveys, sample sizes ranged between 29 and 1124 PCPs. Knowledge and confidence in management of physical (n = 19) and psychosocial effects (n = 12), and surveillance for recurrences (n = 14) were described most often. Generally, a greater proportion of PCPs reported confidence in managing psychosocial effects (24–47% of PCPs, n= 5 studies) than physical effects (10–37%, n = 8). PCPs generally thought they had the necessary knowledge to detect recurrences (62–78%, n = 5), but reported limited confidence to do so (6–40%, n = 5). There was a commonly perceived need for education on long-term and late physical effects (n = 6), and cancer surveillance guidelines (n = 9).ConclusionsPCPs’ knowledge and confidence in cancer survivorship care varies across care domains. Suboptimal outcomes were identified in managing physical effects and recurrences after cancer.Implications for Cancer SurvivorsThese results provide insights into the potential role of PCPs in cancer survivorship care, medical education, and development of targeted interventions.Supplementary InformationThe online version contains supplementary material available at 10.1007/s11764-023-01397-y.

Vacuum massage is a non-invasive mechanical massage technique performed with a mechanical device that lifts the skin by means of suction, creates a skin fold and mobilises that skin fold. In the late 1970s, this therapy was introduced to treat traumatic or burn scars.Although vacuum massage was invented to treat burns and scars, one can find very little literature on the effects of this intervention. Therefore, the aim of this review is to present an overview of the available literature on the physical and physiological effects of vacuum massage on epidermal and dermal skin structures in order to find the underlying working mechanisms that could benefit the healing of burns and scars. The discussion contains translational analysis of the results and provides recommendations for future research on the topic.An extended search for publications was performed using PubMed, Web of Science and Google Scholar. Two authors independently identified and checked each study against the inclusion criteria.Nineteen articles were included in the qualitative synthesis. The two most reported physical effects of vacuum massage were improvement of the tissue hardness and the elasticity of the skin. Besides physical effects, a variety of physiological effects are reported in literature, for example, an increased number of fibroblasts and collagen fibres accompanied by an alteration of fibroblast phenotype and collagen orientation. Little information was found on the decrease of pain and itch due to vacuum massage.Although vacuum massage initially had been developed for the treatment of burn scars, this literature review found little evidence for the efficacy of this treatment. Variations in duration, amplitude or frequency of the treatment have a substantial influence on collagen restructuring and reorientation, thus implying possible beneficial influences on the healing potential by mechanotransduction pathways. Vacuum massage may release the mechanical tension associated with scar retraction and thus induce apoptosis of myofibroblasts. Suggestions for future research include upscaling the study design, investigating the molecular pathways and dose dependency, comparing effects in different stages of repair, including evolutive parameters and the use of more objective assessment tools.Electronic supplementary materialThe online version of this article (doi:10.1186/s41038-016-0053-9) contains supplementary material, which is available to authorized users.

Numerical study of the physical and chemical effects of hydrogen addition on laminar premixed combustion characteristics of methane and ethane

The covalent attachment of various organic molecules on conductive supports including indium tin oxide (ITO) using diazonium chemistry has been known for many years. A commonly used method to achieve this is the electrochemical reduction of diazonium compounds leading to radicals, followed by binding of the radicals to the support. In the present report, an alternative method using ultrasound at different frequencies (20, 582, 863, and 1142 kHz) to induce the surface grafting of nitrobenzene diazonium onto an ITO surface is described. It is shown that the grafting on ITO is more efficient in the lower ultrasonic frequency range that is ascribed to changes in the balance between the physical and chemical effects of cavitation with frequency. Both the physical and chemical effects of cavitation play important roles at all frequencies, but at high ultrasound frequencies, the physical effects are relatively small. At 20 kHz, the physical component, including mass transport, is larger than at higher frequencies, and mechanisms based on these observations have been proposed. Ultrasonic grafting has an advantage over electrografting in that it may provide more control over surface coverage, thus it is suggested that the ultrasonic method is used where the surface concentration of the organic layer must be controlled.

Background Gender dysphoria treatment includes gender-affirming hormone therapy (GAHT). Studies are still lacking on how tocharacterize its effects and impacton transgender people's lives more effectively. Aim To study the physical and psychological effects of GAHT on transgender individuals, assess its impact on their lives, and rate their overall satisfaction. Methods Participants (n = 114; ages 18-62 years; median age 24.0 (21.0 - 33.0) years) included transgender adultsresiding in Portugalwho were undergoing or had undergone hormonal therapy for at least one uninterrupted year. Participants completed an original questionnaire. For most items, an ordinal Likert-style scaleranging from 0 (worst result) to 6 (best result) was used. Descriptive statistics and non-parametric tests, including Pearson's chi-squared test, Wilcoxon signed-rank test, and Mann-Whitney U test were used to analyze categorical and continuous variables, with a significance level set at 0.05. Outcomes The outcomes included desired physical changes rating (perception and satisfaction with changes); side effects of GAHT; the sociopsychological impact of GAHT (on self-esteem, body image, psychological wellbeing, social and family relations); overall satisfaction (with treatment results and medical follow-up). Results The changes classified as the most perceptible in those undergoing masculinizing treatment (Group M) were amenorrhea (6 (5.0-6.0) points) and clitoris enlargement (6 (5.0-6.0) points). These were also the ones rated as the most satisfactory (6 (6.0-6.0) points for amenorrhea and 6 (4.0-6.0) points for clitoris enlargement). On those undergoing feminizing therapy (Group F), the alteration voted as the most perceptible was sperm production decrease (6 (2.0-6.0) points), and the ones classified as the most satisfactory were sperm production decrease (6 (4.0-6.0) points) and spontaneous erections decrease (6 (5.0-6.0) points). Side effects were reported by 89.7% ofGroup M(mood swings were the most common) and 96.3% ofGroup F(decreased libido was the most frequent). The sociopsychological impact of hormonal treatment was significantly positive in all analyzed variables (p<0.001). Overall satisfaction with treatment results and medical follow-up were rated with 5 points and 4.5 points, respectively. Clinical implications This study provides clinicians with more evidence that GAHT may improve the physical, psychological and social health of transgender people seeking medical transition. Strengths and limitations The strengths of the current study include a high participant count relative to the target population, the acquisition of data on previously unexplored variables, and the significance of being one of the few investigations of its kind conducted in Portugal. However, the study has limitations, including differences in participant characteristics, a small sample size for some variables, potential bias due to the retrospective nature of the study, individualized treatment regimens, and the inclusion of participants from different countries, which limit the generalization of the results. Conclusions This study provides further evidence that GAHT is effective, and that its physical effects are satisfactory while resulting in mostly non-severe nor life-threatening side effects. GAHT is an important therapy in gender dysphoria and has consistent results in improving numerous sociopsychological variables.

There is no cure for Duchenne Muscular Dystrophy (DMD); treatment is symptomatic and corticosteroids slow the progression. Side effects of corticosteroids - especially the physical effects - have been described, however patients' and caregivers perception on chronic corticosteroid treatment and their side effects is less well known, in particular with regards to cognition, behaviour, and emotional functioning. The primary aim of this pilot study was to (i) construct a self-report questionnaire to assess the perceived benefits and side effects of corticosteroids for patients with DMD and their parents. Furthermore we aimed to (ii) investigate the psychometric qualities of this questionnaire, (iii) whether there was a difference between parents' and patient's perceptions, and finally (iv) to what extent reported side effects may alter over time. A 23-item questionnaire (SIDECORT: side effect of corticosteroids) was constructed to assess the perception of these benefits and side effects in a systematic manner. In total, 86 patients (aged 5 - 28 years) and 125 of their parents completed the questionnaire. Internal consistency was good. Using factor analyses on the side effect items as reported by parents, two underlying factors were found, with the first factor describing cognitive, behavioural and emotional functioning, and the second factor describing physical functioning. The potential benefits of corticosteroids were highly rated among both parents and patients, although parents rated the importance of the benefits higher than their sons (p = 0.002). Similarly, parents rated the severity of the side effects generally higher than their sons (p = 0.011), especially with regards to the physical side effects (p = 0.014). Based on the parent's perception, the neurodevelopmental side effects generally appeared to decline the longer corticosteroids were used. To our knowledge, this is the first explicit study on perceived cognitive-, behavioural-, and emotional side effects and the allocation of benefits to corticosteroids in DMD. On the basis of our research we suggest a short form questionnaire, which proves to be reliable and valid for research- and clinical practice. This questionnaire could provide useful insights for the care of boys and men with DMD.

Physical and chemical effects of CeF 3 compact in sliding against Hastelloy C in temperature to 700°C

How gluten properties are affected by pentosans