Abstract
Calorimetric titration and NMR experiments in aqueous phosphate buffer (pH 7.2) at 298.15 K have been done to determine the binding mode, complex stability constants and thermodynamics (Δ G°, Δ H°, and TΔ S°) for 1:1 inclusion complexation of water-soluble calix[ n]arenesulfonates (CnAS, n = 4 and 6) and thiacalix[4]arene tetrasulfonate (TCAS) with acethylcholine, carnitine, betaine and benzyltrimethylammonium ion. The results show the inclusion complexations are driven by enthalpy (Δ H° < 0), accompanied by negative entropic changes (Δ S° < 0). The binding affinities (C4AS > C6AS > TCAS) are discussed from the viewpoint of CH–π/π–π interactions, electrostatic interactions and size/shape-fit relationship between host and guest.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
