Abstract
The solubility of disodium 5′-guanylate heptahydrate (5′-GMPNa2) in water-ethanol binary solvent mixtures was measured at temperatures ranging from 278.15K to 323.15K using a dynamic method. The solubility data were correlated by the Apelblat equation, the Combined Nearly Ideal Binary Solvent/Redlich–Kister (CNIBS/R–K) equation and the modified Jouyban–Acree equation, respectively. Results showed that a reasonable match with experimental data is obtained from the Apelblat equation and CNIBS/R–K equation, while the modified Jouyban–Acree equation contains parameters including both solvent composition and temperature. The thermodynamic functions Gibbs free energy, enthalpy and entropy of solution were also calculated based on solubility data of 5′-GMPNa2 determined in binary water+ethanol solvent mixtures by using van’t Hoff equation. The dissolving process is endothermic and the dissolution driving force converts from enthalpy-driving to entropy-driving.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
