Abstract
In this study, two kinds of dual-stimuli-responsive (pH and temperature) hydrogels were prepared through the copolymerization of acrylic acid (hydrophilic monomer) and N-isopropylacrylamide (thermosensitive monomer) with a modified β-cyclodextrin crosslinker or N,N′-methylenediacrylamide in aqueous solution. The swelling properties of these hydrogels, including the pH and temperature dependences of their equilibrium swelling ratios, their shrinking kinetics, and their de-swelling behavior, were investigated. The protein bovine serum albumin was chosen as a model drug to measure their release behavior at different pH values and temperatures. The results revealed that the hydrogel that incorporated the β-cyclodextrin crosslinker exhibits improved properties and could have a wide range of potential uses in biomedicine.
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
