Abstract

Modern Applications in Pharmacy & Pharmacology Thermal Methods of Analysis Nirav Soni* Department of Quality Assurance, India *Corresponding author: Nirav Soni, Department of Quality Assurance, India Submission: October 19, 2017; Published: December 22, 2017 DOI: 10.31031/MAPP.2017.01.000509 ISSN 2637-7756Volume1 Issue2

Highlights

  • Modern Applications in Pharmacy & Pharmacology substances incariably decompose upon heating and this idea of heating a sample to observe weight changes is the underlying principle of Thermo Gravimetric Analysis (TGA)

  • Dynamic TGA: Continuous increased in Temperature Linear with Time

  • The Differential Thermal Analysis (DTA) curve is affected by a larger number of factors than the TG curve

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Summary

Nirav Soni*

C. Instrumentation and Applications of Thermo Gravimetric Analysis (TGA). F. Thermo Mechanical Analysis (TMA) (Figure 1). B. Mass is lost if the substance contains a volatile fraction. A. Provides information about thermal changes that do not involve a change in sample mass. B. More commonly used technique than TGA. C. Two basic types of DSC instruments: heat-flux and power compensation

Thermal Methods
Titration Colorimeter
Factors affecting the DTA curve
Sample Holders Material
Temperature Control
Application Physical chemistry
Power Compensated DSC
Thermo Balance
Deflection of the beam
Heat absorbed or liberated during heating or cooling
Heat Capacity
Three Phase of DSC Curve
What DSC Can Measure?
DSC calibration

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