Thermal and spectroscopic investigation of novel Schiff base, its metal complexes, and their biological activities

Abstract

The complexing behavior of H2L ((N,N’Z,N,N’E)-N,N’-(ethane-1,2-diylbis(oxy)bis(2,1-phenylene)bis(methanylylidene)bis(1-hydrazinylmethanethioamide)) toward the transition metal ions namely Fe(III), Co(II), Ni(II), Cu(II), Cd(II), and Zn(II) have been examined by elemental analyses, magnetic measurements, electronic, IR, and 1H-NMR. Thermal properties and decomposition possibilities of all complexes are suggested. The interpretation of all thermal decomposition stages has been evaluated. The free ligand and its metal complexes have been tested in vitro against Escherichia coli, Proteus vulgaris, Bacillus subtilis, and Staphylococcus aurous bacteria in order to assess their antimicrobial potential. The results indicate that the metal complexes are also found to have more antimicrobial activity than the parent ligand. The proposed structure of complexes. Novel Schiff base and its metal complexes were prepared and characterized based on elemental analyses, IR, 1H-NMR, magnetic moment, molar conductance, and thermal analyses techniques. Complexes of 1:1 [Metal]:[Ligand] ratio for Fe(III), Co(II), Ni(II), Cu(II), and Zn(II) are formed. They are electrolytes in which ligand coordinated to the metal ions in a uni-negative hexa-dentate manner with O2N2 donor sites of the etheric O, and azomethine N atoms and have octahedral geometry.