THERAPEUTIC EFFICACY OF THE DRUG METRACINЕ IN COWS WITH CHRONIC INFLAMMATION OF THE UTERUS

Abstract

The article present the results on the research conducted for the veterinary drug Metracine used in the treatment of cows with chronic endometritis. Two groups were formed: the experimental and control. Before treatment the exudate was taken by three different ways: by a swab-probe applicator – from the vaginal vestibule, by a polystirol pipette – from the uterus and by hand – from the vagina. Pure cultures were isolated from the biological material for further studies of the antibacterial activity. Then we started to determine the therapeutic efficiency. The experimental group experienced the intrauterine administration 20 gr of Metracin once every 48 hours until the clinical recovery. The controls were administered intrauterine Iodosol as directed. Findings showed that the way of sampling influenced neither the quality of biological material nor the results of bacteriological analysis. The difference of methods lies in the convenience of taking samples by a specialist. Bacteriological expertise revealed the presence in the exudate of the following types of microorganisms: Streptococcus spp., Streptococcus pyogenes, Staphylococcus aureus and E.coli which means that there is no interconnection whatsoever between the place of sampling and the type of microorganisms. The study of antibacterial activity of Metracin showed that this drug is destructive for the isolated microflora. The findings show the therapeutic efficacy to be 67.6%.