Abstract
Successful Endodontic therapy aims at thorough debridement of root canals and complete elimination of microorganisms from the root canals. Currently, research in the eld of herbal products has increased due to its varied advantages. Curcumin, a phytochemical obtained from rhizomes of Curcuma longa, shows broad spectrum antimicrobial activity. It is a natural polyphenol that is commonly used as a spice and coloring and avoring agent in South Asian countries. Over the last decade, Curcumin is becoming popular in Endodontics due to its excellent pharmacological attributes like antimicrobial, antifungal, antiviral, antiseptic and anti-oxidant properties. Curcumin also acts as a natural photosensitizer with the ability to provide targeted therapy and has good photophysical properties. It is less cytotoxic compared to sodium hypochlorite and is cost-effective. There is a quest for newer treatment strategies to prevent endodontic failures and Post-treatment apical periodontitis, caused by persistent intraradicular infection. Photodynamic therapy is one such adjunctive therapy found to be effective in the treatment of secondary infections with several invitro studies showing curcumin as an effective photosensitizer in root canal disinfection against resistant gram-positive bacterial species. This review article is a collection of invitro studies describing applications of curcumin in endodontics, its photosensitizing properties, functions and effects of curcumin in Endodontic therapy.
Published Version
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