Therapeutic Effects of CT-guided Microwave Ablation Combined with Cementoplasty in the Treatment of Bone Metastasis

Abstract

Background: The incidence of malignant tumors causing bone metastasis was increasing. Therefore, it was urgent to treat patients with bone metastasis. Objectives: This study aimed to evaluate the role of computed tomography (CT)-guided microwave ablation combined with cementoplasty in the treatment of patients with bone metastasis. Patients and Methods: A total of 20 patients with bone metastasis who were treated with CT-guided microwave ablation combined with cementoplasty were included in this study, according to the inclusion and exclusion criteria. The follow-up data of all patients were collected, and no patients were lost to follow-up during this period. The Quality of Life Questionnaire-Bone Metastases Module 22 (QLQ-BM22), the EuroQOL Five-Dimension Questionnaire (EQ-5D), and the Quality-Adjusted Life Year (QALY) measure were used to assess the treatment effects. Results: Based on the results, 37 operations performed on 20 patients were successful. Minor complications were observed in seven cases. There were significant differences in the QLQ-BM22 scores when comparing the pre-treatment and post-treatment results (P < 0.05). Moreover, the pre-treatment and post-treatment QALY scores exhibited significant differences (P < 0.05). However, there was no significant difference between the pre-treatment and post-treatment EQ-5D scores (P > 0.05). Conclusion: The combination of CT-guided microwave ablation with cementoplasty was proven to be an effective approach in extending the survival time and enhancing the quality of life in patients with bone metastasis.