Therapeutic effect of recombinant human interferon combined with microwave on chronic cervicitis complicated with high-risk HPV infection

Abstract

Objective To observe the therapeutic effect of recombinant human interferon combined with microwave for chronic cervicitis complicated with high-risk human papillomavirus (HPV) infection. Methods 86 cases of chronic cervicitis complicated with high-risk HPV infection treated in our hospital from July, 2015 to June, 2018 were divided into a control group and an observation group by random number table, 43 cases for each group. The control group received microwave treatment, while the observation group recombinant human interferon and microwave treatment. The clinical efficacy, negative conversion rate of HPV infection, recurrence rate, and adverse reactions of the two groups were observed. Results The total effective rate and negative rate of HPV infection were higher and the recurrence rate of HPV infection was lower in the observation group than in the control group (95.35% vs. 79.07%, 65.12% vs. 41.86%, 4.65% vs. 18.60%) (all P 0.05). Conclusion The combination of recombinant human interferon and microwave is safe and feasible for patients with chronic cervicitis complicated with high-risk HPV infection. The healing effect of cervical erosion is good, which is conducive to improving the negative conversion rate of HPV infection and reducing the recurrence rate of HPV infection. Key words: Chronic cervicitis; High-risk HPV infection; Recombinant human interferon; Microwave; Negative HPV infection