Therapeutic Effect of Avishan-e-Shirazi (Zataria Multiflora Boiss) Root Extract on Oxidative Stress Markers in Moderate Asthmatic Patients

Abstract

Avishan-e-Shirazi (Zataria Multiflora Boiss) is a plant widely recognised for its medicinal and culinary purposes. Objectives: To evaluate the therapeutic effect of plant’s root extract on pulmonary function tests and oxidative stress markers among moderate Asthma tic patients. Methods: A total participant of 66 patients with pulmonary disease, 30-40 age, were selected for the 2-month research trial. Individuals were enrolled and distributed equally in two groups, 33 each. In the control group, 53.8% of individual were man, and 46.2% were women. In the treatment group, 49.1% of participants were man, and 50.9% were women. The groups G0 was considered as a control group with no root extract, and group G1 where conventional treatment and root extract were advised to participants. The participants were selected from the Jinnah Hospital, Pakistan. The 5mg/kg/day dried root extract supplements 3 times a day were given to the individuals daily for 2 months. Results: The mean age group of Asthma tic patients enrolled in the study was 35 ± 2.98 years in G0, and in G1, it was 34 ± 3.05. The mean BMI was 31.34 and 30.98 kgm-2 in both groups, respectively. There was a significant improvement in FEV1 levels and MDA enzyme levels with a p-value less than 0.05. The NO2 levels were also better. Similarly, the enzymes thiolase and SOD levels also improved with a p-value less than 0.05 in the treatment group. Conclusions: The current study concluded that Avishan-e-Shirazi root extract could improve the pulmonary function and inflammation among Asthma patients.