Abstract
In contemporary times, the use of traditional remedies is still evident. One of the primary items foremost emphasized today is honey. Aside from its natural sweetener capacity, modern science highlights its potential therapeutic capabilities, including anti-inflammatory and immunoregulatory properties in different Type I Hypersensitivity conditions. This systematic review analyzed nine credible experimental studies to objectify different types of honey and its application and effect in different Type I Hypersensitivity clinical manifestations. The abundance of evidence granting IgE mediated disorders which includes Allergic Asthma, Vernal Keratoconjunctivitis, Allergic Fungal Rhinosinusitis, Allergic Rhinitis, and Atopic Dermatitis in both preclinical and clinical analysis revealed honey to be a contributing factor in suppressing different clinical manifestations of the associated conditions. The systematic review can evaluate and categorize the potential therapeutic capabilities of honey in different IgE-mediated Type I Hypersensitivity Reactions, thus, enabling a comprehended integration towards assisting the application within the clinical setting.
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