Abstract
Metals are important in biochemistry, and the concentrations of many are highly regulated. This prologue introduces the thematic series "Metals in Biology," which includes minireviews on three metals: iron, copper, and selenium. Deficiencies and excesses of all three of these metals cause problems in human health. The three minireviews deal with regulation of iron homeostasis, the roles of copper metabolism in cell regulation and disease, and the functions of selenoproteins.
Highlights
The three minireviews deal with regulation of iron homeostasis, the roles of copper metabolism in cell regulation and disease, and the functions of selenoproteins
The field of biochemistry is often considered as dealing with amino acids and proteins, carbohydrates, lipids, and nucleic acids
A student learns that the proteins act as enzymes, carbohydrates are degraded to provide energy, lipids are used in membranes and provide energy, and nucleic acids are used to control cells through genetics
Summary
The field of biochemistry is often considered as dealing with amino acids and proteins, carbohydrates, lipids, and nucleic acids. This paper is available online at www.jbc.org Metals are important in biochemistry, and the concentrations of many are highly regulated. This prologue introduces the thematic series “Metals in Biology,” which includes minireviews on three metals: iron, copper, and selenium.
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