Abstract
Two amines, serotonin and octopamine, and a pentapeptide, proctolin, function as neurohormones in the lobster nervous system. This review article summarizes findings from this laboratory on: (i) the biosynthesis and further metabolism of the amines; (ii) the localization of amines at a cellular level using immunocytochemical methods; (iii) the physiological effects of the amines and proctolin on exoskeletal muscles and preliminary studies of the molecular basis of these effects; and (iv) explorations on the actions of amines on motoneurons of the ventral nerve cord that show that amines direct the readout of central motor programs for flexion and extension.
Published Version
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