The Weight Assessment and its Relation to Hemophilia Joint Health Score in Hemophilic Patients

Abstract

Background: Haemophilia is a group of hereditary disorders that impair the body's ability to control blood clotting or coagulation. Joint bleeding (hemarthrosis) results in synovial hypertrophy and damage of the cartilage, leading to joint destruction with recurrent bleeding episodes (hemophilic arthropathy). Objective: To assess weight of hemophilic children and correlate the weight to Hemophilia Joint Health Score. Methods: The sample size included was 66 patients with hemophilia in Zagazig city between October 2019 and March 2020. They were categorized according to presence of arthropathy or not [Two groups; one group with hemophilic arthropathy and the other group without hemophilic arthropathy]. All patients were subjected to full history taking including personal history, thorough clinical examination [assessment of vital signs and color, assessment of any bone deformity, pain or muscle weakness and Hemophilia Joint Health Score ] and weight assessment, Results: Our case control study showing male predominance in both groups. In hemophilic arthropathy, 100% (10.68 ± 4.28) and without hemophilic arthropathy 97% (7.17 ± 4.12) and more prevalence of hemophilia A [factor V111 deficiency] in both groups (with H.A.97% & without H.A.78.8%). In addition, our study reported that most common site of bleeding in hemophilic patients rather than big joints affection; gum [18.2%] then gum & teeth [12.1%]. Increased weight was found more in hemophilia with arthropathy than in hemophilia without arthropathy. Conclusion: Our case control study showing male predominance and more prevalence of hemophilia A than B in both hemophilic groups (with or without hemoarthropathy). Weight was significantly increased in hemophilia with arthropathy group than in hemophilia without arthropathy group.