The vertical superior longitudinal fascicle and the vertical occipital fascicle.

Abstract

Association fibers of the human brain have long been considered to exclusively follow an anterior-posterior direction. Using magnetic resonance imaging techniques that allow in-vivo fiber dissection, vertically oriented association fibers have been rediscovered or newly described. Aside from the frontal aslant tract (FAT) in the frontal lobe, the vertical occipital fascicle (VOF) and the vertical portion of the superior longitudinal fascicle system (vSLF) have been studied in recent years. The aim of this review was to give an overview on the current knowledge regarding these two fiber tracts. A review of the available literature in the Medline database was conducted to gather all available publications dealing with either the VOF or the vSLF. One thousand two hundred seventy-three articles were obtained from the literature search of which a total of 71 articles met the final inclusion criteria of this review. We describe the history of the discovery of the respective fiber tract, its anatomical course and its boundaries integrating blunt fiber dissection studies and functional MRI/tractography studies. We discuss the functional properties of the respective fiber tract and its relevance in neurosurgery. The VOF is a fiber tract that has been discovered in the late XIX century and long been forgotten before being rediscovered in the 1970's. It lies lateral to the fibers of the sagittal stratum and mainly connects the superior and inferior occipital lobe. It plays a major role in reading and visual word and language comprehension and is said to be the main link between dorsal and ventral visual streams. The vSLF has many synonyms and is part of the superior longitudinal fascicle system. Recent studies were able to provide more insight into this set of fiber tracts showing distinct connections running from the superior and inferior parietal lobule to the posterior part of the temporal lobe. Its functional role is still not completely cleared. It is said to play a role in visual and auditory semantic language comprehension. It lies directly lateral to the arcuate fascicle. The VOF and the vSLF are vertically oriented fiber tracts connecting the temporo-parieto-occipital region and play a major role in the communication of dorsal and ventral visual streams (VOF), reading (VOF, vSLF) and visual and auditory semantic language comprehension (vSLF). They can consistently be identified using ex vivo blunt dissection techniques and in-vivo fiber tractography. Because of their localization and orientation these two fiber tracts can be combined to a fiber bundle system called posterior transverse system (PTS).