Abstract
Carbonic anhydrase (CA1) enzyme variations of one hundred and forty six specimens of $Mus domesticus$, $Mus macedonicus$ (House mice) and one hundred and twenty specimens of $Rattus rattus$ (Roof rat) and $Rattus norvegicus$ (Brown rat) were examined by the field work conducted in 23 localities in the line of Ankara-BoluZonguldak. It was determined that CA1 was fixed to two different homozygous alleles in both house mouse species. In the roof rat samples, CA1 was fixed to two homozygous alleles at different frequencies in two groups formed according to the colour of the back fur. A single homozygous allele was detected at the CA1 locus of brown rat samples. It was observed that these four species were separated in the UPGMA tree made according to allele frequencies. In this respect, it was evaluated that CA1 could be a molecular marker that can be used to distinguish these species.
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