Abstract

Objective To evaluate the clinical application value of three-dimensional medical image guided ultrasound in the chemotherapy of huge hepatic hemangioma. Methods Seventy-six cases were enrolled in a randomized control study. All cases were randomly divided into two groups (group A and group B). In group A, all cases underwent treatment based on the traditional two- dimensional medical images. Under the assistance of three-dimensional medical image information, preoperative treatment planning was performed in group B. After puncture treatment, therapeutic efficacy was evaluated by color ultrasound during follow-up. Results For treating huge hepatic hemangioma (tumor diameter ≥ 10.0 cm), the insertion number and pingyangmycin dosage in the group B were less than those in the group A [(6.2±0.5) times vs (9.3±0.6) times, t=24.467, P=0.035; (99.2±8.0) mg vs (148.8±9.6) mg, t=34.613, P=0.029]. The success rate of first treatment in the group B was higher than that in group A [73.6%(28/38) vs 100%(38/38), χ2=131.91, P=0.032]. Conclusion For huge hepatic hemangioma, the three-dimensional medical image information can be applied to reduce the insertion number and anesthetics dosage, improving the success rate of first treatment and therapeutic effect. Key words: Huge hepatic hemangioma; Three-dimensional visualization; Ultrasonic guidance; Pingyangmycin; Preoperative treatment planning

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