The Value of Three-Dimensional Tomographic Ultrasound Imaging under Backpropagation Algorithm in the Local Staging Diagnosis of Cervical Cancer

Chenjie Li,Bingjie Liu,Yingying Tian,Ziwen Zhang,M Pallikonda Rajasekaran

doi:10.1155/2022/7017580

Abstract

Based on three-dimensional tomographic ultrasound imaging (TUI) of the backpropagation algorithm, this study evaluated the consistency of three-dimensional TUI technology, pelvic examination, and magnetic resonance imaging (MRI) technology in the local staging diagnosis of cervical cancer, aiming to explore the application value of TUI technology in local staging diagnosis of cervical cancer. The backpropagation algorithm was adopted to segment images, and 35 patients who were confirmed to be cervical cancer by tissue biopsy were included in this study. All selected patients underwent transvaginal TUI examination and pelvic MRI examination. Then, the 2010 Federation Internationale of Gynecologie and Obstetrigue (FIGO) was adopted to determine the clinical stage, and the K index and the percentage of consistency were calculated to evaluate the consistency between TUI and MRI. Comparison of tumor size measurements showed that obvious correlation could be found between MRI and three-dimensional TUI (r = 0.842; P < 0.001), MRI, and clinical examination (r = 0.654; P < 0.001) to the assessment of tumor size. In terms of parauterine invasion, there was a moderate consistency between pelvic examination and MRI (K = 0.413; 95% confidential interval (CI) = 0.085–0.762; the overall coincidence rate (OCR) = 78.0%), and there was good consistency between three-dimensional TUI and MRI (K = 0.655, 95% CI = 0.335–0.949; overall coincidence rate = 87.8%). In terms of vaginal infiltration, pelvic examination and MRI showed moderate consistency (K = 0.434; 95% CI = 0.119–0.733; the OCR = 74.2%), and three-dimensional TUI examination and MRI showed excellent consistency (K = 0.568, 95% CI = 0.274–0.881; the OCR = 81.9%). The accuracy of the backpropagation segmentation algorithm was 82%. The results revealed that the three-dimensional TUI technology and MRI showed a good consistency in assessing parauterine invasion of cervical cancer. When the tumor size was evaluated, there was a clear correlation between three-dimensional TUI scans and MRI. Therefore, three-dimensional TUI technology showed relatively high application value for the local stage of cervical cancer.

Highlights

Cervical cancer is the fifth most common malignant tumor in women, and it is one of the most common causes of cancer deaths in women, especially in underdeveloped countries [1–3]. e treatment of cervical cancer and after surgery mainly depends on the tumor stage [4, 5]
All patients underwent pelvic examination to determine the clinical stage, vaginal tomographic ultrasound imaging (TUI), and magnetic resonance imaging (MRI) to determine the stage. e patients were 26–70 years old, with an average of 51 ± 10 years old, and they all had a history of sexual behavior. ere were 20 cases after menopause and 15 cases before menopause. is study had been approved by the Medical Ethics Committee of the hospital, and the family members of the patients included in the study had signed the informed consent
Comparison of tumor size measurements showed that obvious correlation could be found between MRI and threedimensional TUI (r 0.842; P < 0.001), MRI, and clinical examination (r 0.654; P < 0.001) to the assessment of tumor size

Summary

Introduction

Cervical cancer is the fifth most common malignant tumor in women, and it is one of the most common causes of cancer deaths in women, especially in underdeveloped countries [1–3]. e treatment of cervical cancer and after surgery mainly depends on the tumor stage [4, 5]. E treatment of cervical cancer and after surgery mainly depends on the tumor stage [4, 5]. Most of such staging methods are based on the clinician’s gynecological colposcopy and pelvic palpation. The application of ultrasound imaging technology to the evaluation of cervical cancer staging has attracted special attention in recent years. Compared with conventional twodimensional ultrasound, TUI technology can generally accurately estimate the size and volume of the tumor and show the relationship between the lesion and the surrounding tissue more clearly [11]. It has been reported that the sensitivity and specificity of three-dimensional ultrasound for judging the peritumoral invasion of cervical cancer are 73% and 92%, respectively [12]

Objectives

Methods

Results