Abstract
Abstract It has been suggested that measurement of the plasma enzyme gamma-glutamyl transpeptidase (GGTP) may be useful in the detection of hepatic metastases. To assess the value of GGTP as a screening test for hepatic metastases, 40 cases of gastro-intestinal carcinoma were studied prior to surgery. Ten patients had hepatic metastases, and in 5 of these the plasma GGTP was within normal limits. Abnormal GGTP results were always associated with elevation of the plasma alkaline phosphatase, and preoperative clinical examination of the liver proved to be the most accurate method for the detection of hepatic metastases.
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