Abstract

Objective To evaluate the role of contrast-enhanced ultrasound (CEUS) on the the detection of hepatic metastases in comparison with conventional ultrasonography (US) and contrastenhanced computed tomography (CECT).Methods Ninety-seven patients with hepatic metastases underwent US,CEUS and CECT images.Their detection of hepatic metastases were compared.Results Hepatic metastases showed five enhancement patterns with CEUS,including bolus hyper-enhancement,peripheral rim enhancement,inhomogeneous enhancement with necrosis,hypo-enhancement,isoenhancement with liver parenchyma,all hepatic metastases showed dark defects in portal and delayed phase.The mean number of metastases at CEUS was greater than that of US (2.6±1.9 vs 1.6 ±1.2,P<0.05).The detection of hepatic metastases was 53.4% and 87.1% respectively(P<0.05).CEUS and CECT have no statistically significant difference in the detection of hepatic metastases (P>0.05).Conclusions CEUS can improve detection of hepatic metastases. Key words: Ultrasonography; Microbubbles; Liver neoplasms; Neoplasm metastasis

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