The value of contrast-enhanced ultrasound and contrast-enhanced CT in the differential diagnosis of benign and malignant gallbladder diseases

Abstract

Objective To comparatively analyze the image characteristic of contrast-enhanced ultrasound (CEUS) and contrast-enhanced computed tomography (CECT), and explore the diagnostic value of the two methods in benign and malignant lesions of gallbladder. Methods comparative analysis the image characteristic of CEUS and CECT, the preoperative diagnostic results of 86 cases of gallbladder diseases were confirmed by pathology. Results The enhancement patterns of CEUS and CECT in benign and malignant lesions of gallbladder are similar. The sensitivity, specificity and accuracy of CEUS were 77.9% (53/68), 77.8% (14/18), 77.9% (67/86), respectively. The sensitivity, specificity and accuracy of CECT were 75% (51/68), 55.6% (10/18), 70.9% (61/86), respectively. The sensitivity, specificity and accuracy of the combination of CEUS and CECT were 83.8% (57/68), 55.6% (10/18), 77.9% (67/86), respectively. The accuracy of the combination of CEUS and CECT was higher than that of CECT in the diagnosis of malignant gallbladder lesions [(53.9±10.00) s vs (35.50±6.72) s], the differences were statistically significant (t=6.729, P<0.001). Conclusions The enhancement patterns of CEUS and CECT in benign and malignant gallbladder lesions are similar. The combination of CEUS and CECT is helpful for improving the diagnostic accuracy of malignant gallbladder lesions. CEUS and CECT could corroborate and complement each other, and provide more valuable information for the differential diagnosis of benign and malignant gallbladder lesions. Key words: Ultrasonography; Contrast media; Gallbladder disease