Abstract
Introduction The degree of bone involvement in mandibular squamous cell carcinoma has a significant impact on surgical planning. The purpose of this study was to determine the utility of cone-beam computed tomography (CBCT) for the evaluation of invasion by mandibular squamous cell carcinoma. Methods A retrospective review was conducted to identify subjects treated for oral squamous cell carcinoma (OSCC). All subjects had OSCC adjacent or fixed to the mandible, received preoperative CBCT and multislice computed tomography scan (MSCT), and had resection specimens that included bone. Results Twenty-one subjects met the inclusion criteria. The sensitivity of CBCT was 100% (95% CI 0.75–1), the specificity was 75% (95% CI 0.35–0.97), the positive predictive value was 87% (95% CI 0.66–0.98), and the calculated test accuracy was 91%. The sensitivity of MSCT was 92% (95% CI 0.64–1), the specificity was 100% (95% CI 0.63–1), and the calculated test accuracy was 95%. Discussion CBCT provides meaningful data that may be useful in identifying bony involvement in patients with mandibular squamous cell carcinoma. The utility in delineating erosion versus invasion is limited.
Published Version
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