Abstract
Human plasma is a complex solution containing many proteins, probably hundreds, some of which are present only in trace quantities. The distribution of these proteins in the normal adult shows an amazing degree of uniformity. However, in disease states considerable variation in the quantity of the individual plasma protein components takes place, which is referred to asdysproteinemia. Less frequently, certain qualitatively abnormal proteins may develop as a response to disease, and these proteins are referred to asparaproteins. These variations in plasma proteins in disease have intrigued clinicians since the early salt fractionation of human serum at the turn of the century. In 1921, Howe,1utilizing 21.5% sodium sulfate as a simple method of fractionation, precipitated a protein from serum which was defined as albumin. This quantity of albumin subtracted from the total serum proteins (corrected for nonprotein nitrogen) represented globulin. These two fractions related to the total
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
