Abstract

Reports from China and South Korea have shown improvements in critically ill Covid-19 patients using convalescent plasma from recovered individuals. On 25 March 2020, the Food and Drug Administration announced convalescent plasma guidelines for Covid-19 patients. We collected plasma from one donor by a novel donation method that could safely provide plasma sufficient to 10 patients. Four critically ill patients received convalescent plasma and had well-recognized clinical improvements in 12 to 72 hours. To our knowledge, we are the first to report this novel convalescent plasma collection method. In the view of lack of enough donors, this method can be a breakthrough in the treatment of such a rapidly spreading illness.

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