Abstract

Methods: The proliferative activity of the OSCC was investigated by the doubling time assay. Proliferation essay was done to assess the anti-proliferative effect of Orthosiphon stamineus aqueous extract by treating the human OSCC with 0 – 300 μg/ml of the aqueous extract. The efficacy of Orthosiphon stamineus to inhibit the recovery of the OSCC colonies was measured by clonogenic assay. Caspase-3 activity was investigated using colorimetric assay.

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