Abstract
A feasibility study has been made in the use of optical matched filtering for the automatic detection of cervical cancer cells. With the mean diameter of a malignant cell nucleus used as a detection criterion, it is shown that optimum performance is obtained when the cell images to be cross-correlated are spatially band-pass filtered. The technique is experimentally verified with the cell nuclei modelled by circles and the measurements are shown to agree to within 10% of the theory. Experimental results obtained using imagery of healthy and malignant cells are also presented.
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