Abstract
Introduction Primary intraocular lymphoma (PIOL) is a rare malignancy that affects the ocular system [1,2]. This disease is directly related to primary central nervous system lymphoma (PCNSL). The eyes are involved in approximately 15-25 % of PCNSL while 80% of PIOL eventually develop PCNSL [3,4]. PIOL has been reported to be
Highlights
Primary intraocular lymphoma (PIOL) is a rare malignancy that affects the ocular system [1,2]. This disease is directly related to primary central nervous system lymphoma (PCNSL)
The eyes are involved in approximately 15-25 % of PCNSL while 80% of PIOL eventually develop PCNSL [3,4]
We present the case of a sixty year old woman who developed PIOL after chemotherapy treatment for PCNSL
Summary
Primary intraocular lymphoma (PIOL) is a rare malignancy that affects the ocular system [1,2]. We are reporting the case of a sixty eight year old woman who developed intraocular lymphoma seventeen months after receiving salvage methotrexate therapy for recurrent PCNSL. 2 years from the last treatment, the patient presented with visual impairment in both eyes She was initially diagnosed with vitreatis and received high dose solumedrol 1g daily for 3 days. Presented with headache, dizziness, memory impairment, and imbalance for 5 weeks She was diagnosed with large B-Cell CNS lymphoma by histopathological analysis after brain biopsy. She received 5 cycles of high – dose methotrexate. Histopathological analysis of the vitreous fluid showed a CD3 negative, CD20 positive cell population This diagnosis was consistent with diffuse large B cell lymphoma. The April 2011 MRI of the brain, face and orbits was stable from prior studies
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