Abstract
Intercrosses between divergent lines of domestic animals adapted to different environmental conditions and/or production systems provide unique opportunities for mapping phenotypic trait loci. The strategy resembles the use of interspecific crosses developed for general linkage mapping. We have made an intercross between the wild pig and domestic pigs of the Large White breed. A comprehensive linkage map comprising more than 230 genetic markers has been established. The successful use of this intercross for mapping loci for some monogenic traits (coat color and an intestinal receptor for E. coli K88 pili) as well as quantitative trait loci (QTLs) with major effects of growth and fatness is reviewed.
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