The Ultrastructure of the Coracoacromial Ligament in Patients With Chronic Impingement Syndrome

Abstract

In an ultrastructural study of the cells and matrix of the coracoacromial ligament (CAL) in 11 patients with impingement syndrome (IS), the cells appeared variegated, in contrast to those in normal CALs. Many showed degenerative changes such as lipid inclusions in the cytoplasms or swelling of cytoplasmic organelles, especially in the vicinity of fibrin exudate where the collagenous matrix disappeared. However, some cells had increased cytoplasmic organelles, including an elaborate Golgi apparatus, indicating enhanced synthetic activity. The matrix, instead of consisting of packed collagenous fibers of fairly uniform diameter as seen in the normal CAL, contained collagen fibers of varying diameters and microfibrils. The ultrastructural features of both the cells and the matrix were suggestive of chronic effects of strain on the ligament. In patients with chronic IS, the CAL has been implicated as the likely cause of impingement when no significant bony or articular abnormality exists. This was not substantiated by the present findings. The changes in the CAL in IS are possibly secondary, and are probably induced by alterations in soft-tissue structures of the subacromial compartment.