Abstract
The T-related gene (Trg) of Drosophila is a member of the T-box gene family and displays a high degree of similarity to the vertebrate Brachyury genes. Trg acts down-stream of the terminal gap genes tailless and huckebein and is required for the development of a particular organ, the hindgut. It is expressed throughout embryogenesis, first at the end of the blastoderm stage in the primordium of the hindgut close to the posterior pole of the embryo, then in the differentiating hindgut during gastrulation and organogenesis. A corresponding expression pattern of Trg homologues in the developing hindgut of short germ insects implies that the function of Trg in gut development has been highly conserved during evolution. This conservation in insects and the high similarity between Trg and the chordate Brachyury genes allows speculations about a link between gut parts of insects and notochord of chordates.
Sign-in/Register to access full text options 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a callDisclaimer: All third-party content on this website/platform is and will remain the property of their respective owners and is provided on "as is" basis without any warranties, express or implied. Use of third-party content does not indicate any affiliation, sponsorship with or endorsement by them. Any references to third-party content is to identify the corresponding services and shall be considered fair use under The CopyrightLaw.
