Abstract
The mosquito repellent coils and spray is frequently used to eradicate mosquitoes at home. Those repellents contain transfluthrin components which can interfere with the hormonal and cellular response body when it is used routinely and in the long-term, one of which is the testes. It will affect the quality of sperm production so that it can cause infertility. This research was aimed to know the exposure of transfluthrin in mosquito repellent coils and spray to the sperm quality and testicular histology in rats as a parameter of a fertility assessment. The rats were divided into 5 groups: the control group, the group exposed by mosquito repellent spray for 20 days, 35 days, the group exposed by mosquito repellent coils for 20 days and 35 days. The administered dose for the exposure of the mosquito spray is 3 mL/5 hr/day in rats and repellent coils is 25 gr/5 hr/day. The sperm quality test was done to see the viability, concentration, morphology, and motility, as well as the histopathology of seminiferous tubules and its comparison with control. The result of microscopic sperm quality test in the group of rats that are mosquito repellent coils and spray of 35 days decreased significantly in sperm concentration is 275,58x106/mL, viability is 35,42%, motility is 32,42% and the significant increase in sperm abnormalities is 30% compared to the control group. Treatment with mosquito coiled affected testis weight which decreased at day 20 and reached the lowest weight at day 35 is 1,27 gr. The average number of spermatogenic cells in the seminiferous tubules indicates a significant decrease in the treatment group. The number of spermatogenic cells is decreasing in the 35 days mosquito repellent coils group. Exposure to transfluthrin substances for a long time can decrease the quality and quantity of sperm.
Published Version
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