The Therapeutic Potential of Essential Oils in Cancer Treatment: A Comprehensive Review

Abstract

Essential oils, known for their complex mixture of bioactive compounds, have long been used in traditional medicine and have shown potential in treating various diseases, including cancer. Recent studies highlight their anticancer properties, such as cytotoxic, antiproliferative, and antimetastatic effects. Essential oils contain molecules like terpenes and phenylpropanoids, which induce apoptosis in cancer cells by interfering with cellular signaling pathways. For instance, frankincense oil induces programmed cell death in breast cancer cells, while compounds like curcumin and thymol inhibit the proliferation of colorectal cancer cells. Additionally, certain essential oils prevent metastasis by inhibiting the migration and invasion of cancer cells. Despite promising preclinical results, the effectiveness and safety of essential oils in cancer treatment require further validation through human clinical trials. This review discusses the potential of essential oils as complementary therapies in cancer treatment, emphasizing the need for cautious application under professional supervision due to their concentrated nature and possible adverse effects. The therapeutic promise of essential oils lies in their ability to induce apoptosis, inhibit cell proliferation, and prevent metastasis, underscoring the importance of rigorous research to ensure their safe and effective use in oncology.