Abstract

Abstract A series of N-3-diethylaminopropyl benzamidines has been prepared. The method used was the well-known Pinner synthesis (Pinner, 1892) of the imido-ester hydrochloride and then further reaction with 3-diethylaminopropylamine monohydrochloride. The compounds were tested for histamine-like, antihistamine and adrenergic neurone blocking activity. Some nonspecific antihistamine activity was found; there was no other activity.

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