Abstract

Manometric studies of the pharynx and esophagus in 8 patients with evidence of diabetic neuropathy-gastroenteropathy revealed, in comparison with control patients, marked diminution in the amplitude of pharyngeal contractions, in the percentage of swallows followed by progressive peristalsis in the body of the esophagus, in the amplitude of peristaltic contractions throughout the esophagus, and in the effective lower esophageal intrasphincteric pressure. These observations serve further to delineate and quantitate the nature of the swallowing disorder which had previously been demonstrated cineradiographically in this same group of patients.

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