Abstract
BackgroundLaryngopharyngeal reflux (LPR) is associated with gastroesophageal reflux (GERD) and is known to result in poor asthma control. LPR and asthma frequently co-exist in the same individual. Controlling LPR could be associated with improved asthma control. The supraglottic index (SGI) is a clinically applied visual scale, which correlates with the presence of LPR. The role of SGI in monitoring LPR therapy in individuals with asthma is unknown. ObjectiveCan the SGI be used over time to assess the presence of LPR in patients with asthma, and does the SGI improve with LPR treatment? MethodsThis is a pilot study of 15 participants with asthma. Those without evidence of LPR by SGI measurement were assigned to the observation arm. Those with LPR were assigned to the treatment arm and were treated with either standard of care LPR treatment (antacids and behavioral management) or a novel therapy (upper esophageal assist device). ResultsThe SGI remained stable in individuals with asthma undergoing observation over 8 weeks. The SGI improved in participants with asthma treated for LPR (p=0.024). ConclusionThe SGI is a readily available clinical tool to assess the presence of LPR and monitor its therapy in asthma.
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