Abstract

As demonstrated, products of papain degradation of immune gamma-globulin do not fixate the complement in the presence of specific antigen; however, they competitionally inhibit the complement fixation reaction by unchanged serum and specific antigen. To ascertain the serological activity of papain-degradated antibodies, a method of inhibiting the complement fixation reaction has been developed, the sensitivity of which is 80–100 times that of the method of precipitation reaction inhibition used for this purpose formerly.

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