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Abstract
SummarySome rabbits immunized with 2 M ammonium sulfate precipitable fraction of rabbit submaxillary gland extract in Freund adjuvant developed complement fixing and precipitating antibodies and a cutaneous hypersensitivity of the delayed type, specific for immunizing antigen. Sera which yielded salivary gland specific precipitation and complement fixation reactions also yielded comparable reactions with rabbit saliva. Studies of the complement fixation and precipitation reactions pointed to the presence of distinct auto- and isoantibodies in different immune sera. The relevant observations may be summarized as follows. 1. Autoantibodies. Some rabbit antisera fixed complement and yielded lines of precipitation in Ouchterlony plates with extracts and globulins of submaxillaries of all rabbits tested including the antibody producing rabbits' own submaxillaries and saliva. 2. Isoantibodies, a) Some rabbit antisera yielded precipitation reactions with pooled rabbit submaxillary globulins and with antigens pre...
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Schedule a callMore From: Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.)
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