Abstract
The study of the anti-exudative activity of dezapur on the model of acute pulmonary edema in rats
Highlights
The aim of our work was a profound study of the pharmacological action of a new chemical substance under the conditional name of Dezapur, namely identification of its anti-exudative activity on the model of the experimental pulmonary edema in rats
A marked hypoxia develops, it leads to dysfunction of the ventilatory lung capacity and abnormal volume increase of the intervascular fluid in the lungs causing development of the alveolar edema and increased lung mass ratio (LMR)
All animals were divided into 4 groups (6 animals in each group): group 1 – intact control (IC); group 2 – control pathology (CP), animals treated with distilled water in the volume of 1 ml; group 3 – animals received Dezapur in the effective dose of 10 mg/kg; group 4 – animals received Indomethacin in the effective dose of 5 mg/kg
Summary
The aim of our work was a profound study of the pharmacological action of a new chemical substance under the conditional name of Dezapur, namely identification of its anti-exudative activity on the model of the experimental pulmonary edema in rats
Sign-in/Register to view highlights & summary Sign-in/Register to access full text options 
Free) 
Talk to us
Join us for a 30 min session where you can share your feedback and ask us any queries you have
Schedule a call
