Abstract
The article presents the data of the pharmacognostic research of the plant raw material from the overground parts of Medicago falcata L. subsp. romanica (Prodan) O. Schwarz & Klink. The aim of our work was to determine the composition and the quantitative content of the components from the true coumarins class revealing the anticoagulation effect. The plant raw material was collected in the period of active vegetation. It was dried in a draught at the temperatures up to 40°C. For the first time gas-liquid chromatography with mass spectrometric detection of the raw material extract has been performed. The components have been identified by the library of mass spectra NIST 05 and WILEY 2007 together with the programmes for identifying AMDIS and NIST. The internal standard method has been used for quantitative calculations. The data obtained have shown the presence of 66 compounds, and 38 of them have been identified and quantitatively characterized. The extract from the raw material of Medicago falcata L. subsp. romanica (Prodan) O.Schwarz & Klink contains a number of biologically active substances in the native form – fatty acid and primary products of biosynthesis. Dihydrocoumarin and coumarin in the corresponding amounts have been identified from compounds of the true coumarin class in the overground parts of alfalfa (M. falcata L. subsp. romanica).
Highlights
Medicago L. genus has 100 types of the world flora, 24 of them are wide spread on the territory of Ukraine
The aim of this work is the pharmacognostic study of the composition and the quantitative content of free coumarins in the overground parts of the raw material of the representative of Medicago L. genus – Medicago falcate L. subsp. romanica (Prodan) O
The data obtained for free coumarins are given in Table
Summary
Medicago L. genus has 100 types of the world flora, 24 of them are wide spread on the territory of Ukraine. These plants were distributed from the natural habitat in South West Asia to many countries due to the armies of conquerors. In the German ethnoscience the aqueous infusion of alfalfa is used in diabetes mellitus and dysfunctions of the thyroid [5, 11]. It has a diuretic, antibacterial, general tonic action, assists renewal of the cartilaginous tissue of joints of the backbone [9, 10]
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