Abstract

The fast development of metal nanoparticles capped with organic monolayer is offering the possibility to create a whole new variety of products with novel characteristics, functions and applications. Among these, the nanoparticles covered with carbohydrates (glyconanoparticles) constitute a good bio‐mimetic model of carbohydrate presentation at the cell surface and are currently centered on many glycobiological and biomedical applications. In this paper, a series of novel D‐xylose gold nanoparticles with the linkers of alkyl or polyethylene glycol have been synthesized via D‐xylosethiols formed self‐assembled monolayers with gold nanoparticles (circa 5 nm diameter). D‐xylosethiols were characterized by FTIR, NMR. The characterizations of Xylose‐modified gold nanoparticles by TEM, UV‐Vis, FTIR and colorimetry techniques and bioassay are investigated.This work is supported by the National Taipei University to SMC and KYH (NTUT 100‐140‐01, NTUT 99‐140‐04)

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