Abstract
Cancer: a global problem Cancer, a disease initiated by uncontrolled cell division in any part of the body, is a major public health problem globally, includ ing in developed countries, as a cause of mor bidity and mortality [1]. According to Global Cancer Control, approximately 12.7 million new cancer patients were diagnosed, with 7.6 million deaths, in 2008 and this is pre dicted to increase 21.4 million by 2030 [2]. Conventional treatment strategies for cancer include surgery, radiation therapy, chemo therapy or combination of these. However, these strategies have several limitations including damaging healthy cells, nonspeci ficity, toxicity of anticancer drugs, poor bio availability, fast clearance and restrictions in the case of metastasis. According to the highlights published in May 2008 by BCC Research.com, the market value of global can cer therapeutics was US$47.3 billion in 2008 and expected to increase US$110.6 billion by 2013 with a compound annual growth rate of 12.6% [3]. Therefore, it is immediately necessary to establish an economically cheaper alterna tive treatment strategy for the development of cancer disease rather than the orthodox exist ing approaches. In this context, our group has designed and developed green synthe sized silver nanoparticles (SNPs) that show multifunctional activities for biomedical applications using a nanomedicinal approach.
Published Version
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